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Gastric dysplasia causing gastric outlet obstruction
Rahul Kumar1, Ipsit Ilahi1, Tripti Prajapati2
1Department of Surgical Oncology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
BMJ Case Reports
|July 28, 2021
Summary
Gastric dysplasia, a condition with atypical cells, rarely causes gastric outlet obstruction (GOO). This case report details a young woman whose gastric dysplasia presented as GOO, a rare initial symptom.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Gastric dysplasia involves atypical cells in the gastric mucosa, typically without invasion.
- Gastric outlet obstruction (GOO) is usually linked to advanced gastric cancer, especially in delayed medical care settings.
- Dysplasia rarely causes significant obstruction.
Observation:
- A young woman presented with symptoms of gastric outlet obstruction (GOO).
- Endoscopic and radiological evaluations revealed nodular thickening in the gastric antrum causing GOO.
- Endoscopic biopsy confirmed gastric dysplasia.
Findings:
- Histopathological examination of the resected stomach confirmed dysplasia without invasion beyond the lamina propria.
- This presentation of gastric dysplasia as GOO is highly unusual.
- This is potentially the first reported case of gastric dysplasia presenting as GOO.
Implications:
- This case expands the known clinical presentations of gastric dysplasia.
- It highlights the importance of considering less common causes of GOO, even in the absence of invasive cancer.
- Further research may be needed to understand the mechanisms behind dysplasia-induced GOO.
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