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Updated: Oct 26, 2025

Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration
Published on: May 24, 2016
Newborn With Severely Depressed Left Ventricular Function: Acute Myocardial Infarction in a Newborn
Neha Ahluwalia1, Robert H Pass1, Scott I Aydin1
1Division of Pediatric Cardiology and Pediatric Critical Care Medicine, Department of Pediatrics, Icahn School of Medicine at Mount Sinai and Kravis Children's Hospital at Mount Sinai, Mount Sinai Medical Center, New York, New York.
Abstract:
We describe a rare case of spontaneous coronary artery thrombosis in a newborn leading to rapid severe ventricular dysfunction. Early diagnosis is critical and management strategies are varied including hemodynamic support with extracorporeal membrane oxygenation, systemic/local thrombolytic therapy with tissue plasminogen activator, or surgical thrombectomy. (Level of Difficulty: Advanced.).
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