Related Experiment Video
Updated: Oct 26, 2025

Models of Bone Metastasis
Published on: September 4, 2012
Apical Sparing Pattern of Longitudinal Strain and Positive Bone Scintigraphy in Metastatic Myocardial Calcification
Kathleen W Zhang1, Justin S Sadhu1, Brent W Miller2
1Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri.
Abstract:
An apical sparing pattern of longitudinal strain and positive radionuclide bone scintigraphy are believed to be specific for the diagnosis of transthyretin cardiac amyloidosis. We report on a young woman with apical sparing of longitudinal strain and positive bone scintigraphy who was found to have metastatic myocardial calcification at autopsy. (Level of Difficulty: Intermediate.).
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