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Updated: Oct 26, 2025

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
Published on: June 13, 2019
Rare Presentations of Rapidly Growing Liposarcomas
Arifa Javed1, Jafar Haghshenas1, Scott Sholem1
1Department of Surgery, St. Joseph's Regional Medical Center, Paterson, NJ, USA.
Abstract:
Liposarcomas (LSs) are a rare form of malignant tumors. They are the most common primary neoplasms of the retroperitoneum. While these tumors rarely metastasise, they are characterised by local recurrence and infiltration. Moreover, most are asymptomatic and hence grow to massive sizes before becoming symptomatic. Here, we report two unique cases of giant retroperitoneal liposarcomas seen in our urban tertiary care centre. The first case is that of a 53-year Dominican male, who developed a massive recurrence of his retroperitoneal LS within a span of just two months after initial resection ̶ an exceedingly rare occurrence. The second case is that of a 67-year Peruvian female, who was found to have a retroperitoneal LS, causing complete displacement of the viscera in her right hemiabdomen. Key Words: Liposarcomas, Recurrence, Retroperitoneum.

