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2D MXene Nanomaterials for Versatile Biomedical Applications: Current Trends and Future Prospects
Beibei Lu1,2, Zhenye Zhu1,2, Biyuan Ma1,2
1School of Materials Science and Engineering, Harbin Institute of Technology (Shenzhen), Shenzhen, 518055, China.
Small (Weinheim an Der Bergstrasse, Germany)
|July 29, 2021
Summary
Two-dimensional (2D) MXene nanomaterials, derived from MAX phase ceramics, show great promise for advanced biomedical applications. This review highlights their preparation, surface modification, and potential in cancer treatments, drug delivery, and bioimaging.
Area of Science:
- Materials Science
- Biomedical Engineering
- Nanotechnology
Background:
- Research on 2D nanomaterials is nascent, with limited exploration of their biomedical applications.
- 2D MXenes, derived from MAX phase ceramics, are emerging inorganic nanosystems with significant biological potential.
- Understanding the interaction between 2D MXenes and biological systems is crucial for their clinical translation.
Purpose of the Study:
- To review the latest advancements in 2D MXene nanomaterials for cutting-edge biomedical applications.
- To discuss preparation, surface modification, and diverse therapeutic and diagnostic uses of 2D MXenes.
- To explore future trends and prospects for 2D MXenes in clinical settings, particularly in oncology.
Main Methods:
- Literature review of recent studies on 2D MXene nanomaterials.
- Synthesis and surface modification strategies for biomedical applications.
- Evaluation of applications including drug delivery, antibacterial activity, bioimaging, sensing, and biocompatibility.
Main Results:
- 2D MXenes exhibit unique properties suitable for various biomedical applications.
- Preparation and surface modification techniques are advancing for enhanced biocompatibility and functionality.
- Promising results in drug delivery, antibacterial activity, bioimaging, and sensing have been reported.
Conclusions:
- Emerging 2D MXenes are poised to play a significant role in next-generation cancer treatments.
- Further research into their clinical translation and long-term biocompatibility is warranted.
- 2D MXenes represent a promising platform for future innovations in nanomedicine.
