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Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

480
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
480
Psychosurgery01:30

Psychosurgery

150
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
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Electroconvulsive Therapy01:30

Electroconvulsive Therapy

304
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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Related Experiment Video

Updated: Oct 26, 2025

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
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Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

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Advances in Epilepsy Surgery.

Fernando N Galan1, Alexandra D Beier2, Raj D Sheth1

  • 1Deptartment of Neurology, Mayo Clinic & Nemours Children's Health System, Jacksonville, Florida.

Pediatric Neurology
|July 30, 2021
PubMed
Summary
This summary is machine-generated.

Pediatric epilepsy surgery is an underused treatment for intractable seizures. Evaluating risks versus benefits of surgery is crucial for children with epilepsy unresponsive to medication.

Keywords:
Epilepsy surgeryIntractable epilepsyLocalization related epilepsyPediatric epilepsy

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Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
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A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery
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Last Updated: Oct 26, 2025

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
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Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
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A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery
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Area of Science:

  • Pediatric Neurology
  • Neurosurgery

Background:

  • Intractable epilepsy significantly impacts children's lives and incurs societal costs.
  • Despite advances in antiseizure medications, many pediatric cases remain refractory.
  • Epilepsy surgery offers a long-standing, yet underutilized, treatment option for intractable pediatric epilepsy.

Purpose of the Study:

  • To review the literature and expert opinions on pediatric epilepsy surgery.
  • To highlight epilepsy surgery as an underused modality for treating children with intractable epilepsy.
  • To provide guidance on patient selection, evaluation, and surgical options for pediatric epilepsy.

Main Methods:

  • Literature review and synthesis of published opinions.
  • Discussion of patient selection criteria and diagnostic evaluations.
  • Analysis of surgical outcomes and emerging treatment modalities.

Main Results:

  • Pediatric epilepsy surgery is an underutilized but effective treatment for intractable epilepsy.
  • The risks associated with surgery and medication non-efficacy must be weighed against potential surgical benefits.
  • Various surgical approaches and newer techniques like MRI-guided laser therapy are available.

Conclusions:

  • Epilepsy surgery is a valuable, underused option for pediatric intractable epilepsy.
  • A systematic approach to patient evaluation and selection is essential for successful surgical outcomes.
  • Emerging technologies offer new possibilities for treating refractory epilepsy in children.