Related Experiment Video
Updated: Oct 26, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Modifiable Risk Factors for Chronic Kidney Disease in Adulthood seen among School Children in Asaba
O C Ajaegbu1, B U Ezeonwu1, O D Emeagui1
1Department of Paediatrics, Federal Medical Centre, Asaba, Delta State, Nigeria.
Insights
Chronic kidney disease (CKD) risk factors like obesity and proteinuria are prevalent in Nigerian primary school children, particularly those from higher socioeconomic backgrounds and private schools. Early detection and intervention are crucial for preventing CKD in this vulnerable population.
Area of Science:
- Nephrology
- Pediatrics
- Public Health
Background:
- Chronic kidney disease (CKD) poses a significant health burden, especially in developing nations like Nigeria.
- Limited access to affordable renal replacement therapy for end-stage renal disease (ESRD) necessitates a focus on preventive nephrology in children.
- Early detection and management of CKD risk factors in children are vital to curb the rising prevalence.
Purpose of the Study:
- To assess the prevalence of modifiable CKD risk factors (hypertension, obesity, proteinuria, microalbuminuria) in primary school children in Asaba, Nigeria.
- To investigate the association between these risk factors and children's socioeconomic status (SES) and school type.
- To inform targeted public health interventions for pediatric CKD prevention.
Main Methods:
- A cross-sectional descriptive study involving 400 primary school students in Asaba.
- Urine analysis using dipsticks to detect proteinuria and microalbuminuria.
- Measurement of weight, height, body mass index (BMI), and blood pressure for each participant.
Main Results:
- Prevalence rates were 3.5% for hypertension, 9.8% for obesity, 17.3% for proteinuria, and 18.8% for microalbuminuria.
- Obesity and proteinuria showed significant positive trends with increasing SES and were more common in private schools.
- Hypertension and microalbuminuria prevalence were not significantly associated with SES or school type.
Conclusions:
- Obesity and proteinuria, key risk factors for adult CKD, were disproportionately found in children from higher socioeconomic backgrounds.
- Findings highlight the need for targeted screening and preventive strategies in specific child populations.
- Preventive nephrology programs focusing on modifiable risk factors in childhood are essential for long-term kidney health.
Background:
The burden of chronic kidney disease (CKD) is huge especially in developing countries like Nigeria. In Nigeria, treatment modalities for ESRD (renal replacement therapy) are not readily available and, where available, they are not affordable. Consequently, preventive nephrology aimed at early detection and prompt treatment of children with CKD risk factors has become the viable alternative in curbing this rising problem.
Aim:
To determine the burden of some modifiable risk factors for CKD in adulthood (hypertension, obesity, proteinuria, and microalbuminuria) among primary school children in Asaba and to ascertain if there is any association between the prevalence of such modifiable risk factors and socio-economic status (SES) or school type of the children.
Subjects And Methods:
This is a cross-sectional descriptive study involving 400 primary school students in Asaba. Albuminspecific dipstick urinalysis was used to determine microalbuminuria while standard dip-stick urinalysis was used to determine proteinuria. Weight, height, body mass index (BMI) and blood pressure were measured for each child.
Results:
Modifiable risk factors for CKD were found among primary school children in Asaba with prevalence rates of 3.5%, 9.8%, 17.3%, and 18.8% for hypertension, obesity, proteinuria and microalbuminuria respectively. Obesity and proteinuria showed significant linear trend with SES (p < 0.005 and P=0.004, respectively) and were significantly higher in those that attended private schools compared with public schools (P < 0.005 and P=0.004, respectively). The burden of hypertension and microalbuminuria among the children were not influenced by their SES (p =0.94 and P= 0.99, respectively) or the school type the children attended (P=0.35 and P=0.44, respectively).
Conclusion:
Obesity and proteinuria which are known risk factors for CKD in adulthood were noted mostly among children of high socioeconomic status.
Related Concept Videos
Chronic Kidney Disease I: Introduction
Chronic Kidney Disease II: Clinical Manifestations
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Chronic Kidney Disease III: Interprofessional Care
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration

