Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1000
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1000
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

771
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
771
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

899
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
899

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perimetric Outcomes of Melbourne Rapid Field Perimetry in Patients With Glaucoma: A Systematic Review and Meta-Analysis.

Journal of glaucoma·2026
Same author

Locally-affiliated authorship in global eye health research conducted in Sub-Saharan Africa between 2003 and 2022.

Eye (London, England)·2026
Same author

Outcomes of Minimally Invasive Glaucoma Surgery, Trabeculectomy, and Tube Shunt Surgery in Secondary Glaucoma: IRIS® Registry Analysis.

American journal of ophthalmology·2026
Same author

Comparison of Glaucoma Surgery Incidence and Outcomes in Pigmentary and Primary Open-Angle Glaucoma: IRIS® Registry Analysis.

Ophthalmology·2026
Same author

Development of Perimetric Glaucoma and Outcomes of Interventions in Pseudoexfoliation Syndrome with and without Ocular Hypertension.

Ophthalmology·2026
Same author

Corneal Endothelial Keratoplasty After Glaucoma Treatment: An American Academy of Ophthalmology IRIS® Registry Analysis.

Ophthalmology. Glaucoma·2026
Same journal

Factors Associated With Retinal Nerve Fiber Layer Asymmetry in Primary Open-Angle Glaucoma Among Individuals of African Ancestry.

Journal of glaucoma·2026
Same journal

Haploinsufficiency of PITX2 in Four Chinese Families with Axenfeld-Rieger Syndrome.

Journal of glaucoma·2026
Same journal

Intraocular Pressure-Lowering Effect of Omidenepag Isopropyl as a Predictor for the Efficacy of Laser Trabeculoplasty.

Journal of glaucoma·2026
Same journal

Comparative Outcomes Between Micropulse and Slow-Coagulation Transscleral Cyclophotocoagulation in Eyes With Good Visual Acuity.

Journal of glaucoma·2026
Same journal

Machine Learning With Optical Coherence Tomography for Glaucoma Diagnosis.

Journal of glaucoma·2026
Same journal

GATT-First Surgical Sequence Reduces Complications in Combined Phacoemulsification-GATT Surgery for Glaucoma.

Journal of glaucoma·2026
See all related articles

Related Experiment Video

Updated: Oct 26, 2025

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.5K

Lessons Learned From 2 Large Community-based Glaucoma Screening Studies.

Natasha N Kolomeyer1,2, Leslie J Katz1,2, Lisa A Hark3,4

  • 1Glaucoma Service.

Journal of Glaucoma
|August 2, 2021
PubMed
Summary
This summary is machine-generated.

Community screening for glaucoma has faced challenges. Lessons from two large studies offer insights for improving screening for asymptomatic diseases in vulnerable populations.

More Related Videos

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
13:47

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

9.5K
Subjective Refraction Test Using a Smartphone for Vision Screening
05:36

Subjective Refraction Test Using a Smartphone for Vision Screening

Published on: October 18, 2024

1.2K

Related Experiment Videos

Last Updated: Oct 26, 2025

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.5K
Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
13:47

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

9.5K
Subjective Refraction Test Using a Smartphone for Vision Screening
05:36

Subjective Refraction Test Using a Smartphone for Vision Screening

Published on: October 18, 2024

1.2K

Area of Science:

  • Ophthalmology
  • Public Health
  • Preventive Medicine

Background:

  • Community-based screening programs often struggle with low glaucoma prevalence and follow-up barriers.
  • Effective screening for asymptomatic conditions in vulnerable groups remains a significant public health challenge.

Purpose of the Study:

  • To highlight key lessons learned from two major prospective trials on glaucoma screening and follow-up.
  • To identify broader applicability of these lessons to screening for other asymptomatic diseases in underserved communities.

Main Methods:

  • Review of findings from the Philadelphia Telemedicine Glaucoma Detection and Follow-up Study.
  • Analysis of outcomes from the Screening To Prevent Glaucoma Study.

Main Results:

  • Screening limitations and patient follow-up issues hinder the success of community-based glaucoma detection.
  • Telemedicine approaches and structured follow-up protocols show potential for improving screening efficacy.

Conclusions:

  • Lessons from glaucoma screening trials can inform strategies for other asymptomatic disease screenings in vulnerable populations.
  • Addressing barriers to care and optimizing screening methods are crucial for public health interventions.