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Updated: Oct 26, 2025

Combinatorial Synthesis of and High-throughput Protein Release from Polymer Film and Nanoparticle Libraries
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Geared Toward Applications: A Perspective on Functional Sequence-Controlled Polymers
Cangjie Yang1, Kevin B Wu1, Yu Deng1
1Department of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467, United States.
Abstract:
Sequence-controlled polymers are an emerging class of synthetic polymers with a regulated sequence of monomers. In the past decade, tremendous progress has been made in the synthesis of polymers with the sophisticated sequence control approaching the level manifested in biopolymers. In contrast, the exploration of novel functions that can be achieved by controlling synthetic polymer sequences represents an emerging focus in polymer science. This Viewpoint will survey recent advances in the functional applications of sequence-controlled polymers and provide a perspective on the challenges and outlook for pursuing future applications of this fascinating class of macromolecules.
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