Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Heart Rates01:31

Regulation of Heart Rates

2.8K
The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
2.8K
Decreased pulse rate01:14

Decreased pulse rate

654
Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
654
Factors Affecting Respiration01:24

Factors Affecting Respiration

8.0K
Respiration is a crucial physiological function involving exchanging oxygen (O2) and carbon dioxide (CO2) between an organism and its environment. Various factors can impact this essential process:
8.0K
Physiology of Respiration II: Neurogenic Control of Respiration01:22

Physiology of Respiration II: Neurogenic Control of Respiration

1.2K
The neurogenic control of respiration coordinates various neural networks and pathways to regulate breathing rate and depth, meeting the body's oxygen and carbon dioxide exchange requirements. This system adapts to physiological and environmental conditions, ensuring optimal breathing patterns.
Central Control
The brainstem is the primary site of central control, hosting respiratory centers:
1.2K
The Parasympathetic Nervous System01:14

The Parasympathetic Nervous System

111.4K
Overview
111.4K
Chemical Factors Affecting Respiration Centers01:31

Chemical Factors Affecting Respiration Centers

1.4K
Chemical factors such as changing CO2, O2, and H+ levels in arterial blood play a critical role in influencing respiration depth and rates. These variations are detected by chemoreceptors—specialized sensors located in two primary body areas. Central chemoreceptors are found throughout the brain stem, including the ventrolateral medulla, while peripheral chemoreceptors are located in the aortic arch and carotid arteries.
CO2 has a potent influence on respiration and is strictly regulated....
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Central pattern generator based on self-sustained oscillator coupled to a chain of oscillatory circuits.

Chaos (Woodbury, N.Y.)·2022
Same author

Modification of Joint Recurrence Quantification Analysis (JRQA) for assessing individual characteristics from short EEG time series.

Chaos (Woodbury, N.Y.)·2021
Same author

Wavelet skeletons in sleep EEG-monitoring as biomarkers of early diagnostics of mild cognitive impairment.

Chaos (Woodbury, N.Y.)·2021
Same author

Autonomic control is a source of dynamical chaos in the cardiovascular system.

Chaos (Woodbury, N.Y.)·2020
Same author

Network physiology in insomnia patients: Assessment of relevant changes in network topology with interpretable machine learning models.

Chaos (Woodbury, N.Y.)·2020
Same author

Is dynamic desaturation better than a static index to quantify the mortality risk in heart failure patients with Cheyne-Stokes respiration?

Chaos (Woodbury, N.Y.)·2018
Same journal

Exploring mechanisms for reversal of flow in tunicate hearts.

Chaos (Woodbury, N.Y.)·2026
Same journal

State estimation in spatiotemporal chaos via low-rank StatFEM.

Chaos (Woodbury, N.Y.)·2026
Same journal

Universal response functions in driven dissipative tunneling dynamics.

Chaos (Woodbury, N.Y.)·2026
Same journal

A network-based approach to characterize the dynamics of the coupling field of thermoacoustic oscillators in annular geometry.

Chaos (Woodbury, N.Y.)·2026
Same journal

Data-driven soliton manifold approximations for dark and bright waves: Some prototypical 1D case examples.

Chaos (Woodbury, N.Y.)·2026
Same journal

Gap junction architecture and synchronization clusters in the thalamic reticular nuclei.

Chaos (Woodbury, N.Y.)·2026
See all related articles

Related Experiment Video

Updated: Oct 26, 2025

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography
09:13

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography

Published on: April 28, 2020

6.8K

Decrease of coherence between the respiration and parasympathetic control of the heart rate with aging.

V I Ponomarenko1, A S Karavaev1, E I Borovkova2

  • 1Kotelnikov Institute of Radioengineering and Electronics of Russian Academy of Sciences, Saratov Branch, Zelyonaya Street, 38, Saratov 410019, Russia.

Chaos (Woodbury, N.Y.)
|August 3, 2021
PubMed
Summary
This summary is machine-generated.

Coordinated heart rate and respiration dynamics show decreased coherence with age. This age-related decline in autonomic control impacts physiological synchrony across awake and sleep states.

More Related Videos

Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues
08:41

Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues

Published on: June 3, 2019

10.1K
Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
04:20

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure

Published on: October 1, 2019

6.0K

Related Experiment Videos

Last Updated: Oct 26, 2025

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography
09:13

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography

Published on: April 28, 2020

6.8K
Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues
08:41

Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues

Published on: June 3, 2019

10.1K
Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
04:20

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure

Published on: October 1, 2019

6.0K

Area of Science:

  • Human physiology
  • Autonomic nervous system
  • Cardiorespiratory coupling

Background:

  • Understanding the coordinated behavior of human bodily systems is crucial for physiological insights.
  • The interplay between heart rate and respiration, particularly their coordinated dynamics, is of significant scientific interest.
  • Autonomic control of heart rate is a key regulator of cardiovascular function.

Purpose of the Study:

  • To investigate the coherence between respiration and autonomic heart rate control across different age groups.
  • To examine how this coherence changes in various physiological states: awake, REM sleep, and deep sleep.
  • To explore the impact of aging on cardiorespiratory coupling.

Main Methods:

  • Analysis of coherence between respiratory patterns and heart rate variability in different age cohorts.
  • Data collection across three distinct states: wakefulness, rapid eye movement (REM) sleep, and non-REM (deep) sleep.
  • Comparative analysis of coherence dynamics across age groups and sleep stages.

Main Results:

  • A consistent, monotonic decrease in cardiorespiratory coherence was observed with advancing age.
  • Age-related alterations in the autonomic control of circulation are suggested as the underlying cause.
  • The dynamics of coherence during the transition from wakefulness to sleep were qualitatively similar across all age groups studied.

Conclusions:

  • Aging is associated with reduced cardiorespiratory coherence, likely due to changes in autonomic regulation.
  • The findings highlight age-dependent modifications in the synchronization between breathing and heart rate control.
  • Sleep transitions reveal consistent patterns of cardiorespiratory coupling dynamics irrespective of age.