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Insights from Monitoring Aspirin Adherence: A Medication Adherence Cascade Tool
Heather L Wheat1, Elliane Irani2, Joel Hughes3
1Department of Medicine, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Patient Preference and Adherence
|August 4, 2021
Summary
Aspirin adherence in heart failure patients was suboptimal at 82.2%, despite its ease of use. A new tool, the Medication Adherence Cascade Tool (MACT), is proposed to improve patient adherence.
Area of Science:
- Cardiology
- Pharmacology
- Health Services Research
Background:
- Medication adherence is crucial for cardiovascular disease (CVD) management.
- Barriers exist throughout the medication adherence cascade: prescribing, obtaining, taking, and maintaining.
- Aspirin presents fewer adherence barriers due to its OTC status, low cost, and once-daily dosing.
Purpose of the Study:
- To report on aspirin adherence rates in patients with heart failure.
- To introduce the Medication Adherence Cascade Tool (MACT) for clinical use.
- To identify factors influencing aspirin adherence.
Main Methods:
- Aspirin adherence was tracked using electronic pillboxes in 151 heart failure patients.
- Statistical analyses included frequency analysis, independent t-tests, ANOVA, and chi-square tests.
- Demographic characteristics were assessed for differences in adherence.
Main Results:
- Overall mean aspirin adherence was 82.2%.
- Adherence rates varied: 11.9% (≤50%), 18.5% (50-80%), and 69.5% (≥80%).
- Higher adherence was noted in White patients (84.47%) vs. Black patients (73.53%) and older adults (≥70 years: 87.00%) vs. younger adults (<70 years: 77.49%).
Conclusions:
- Aspirin adherence remains suboptimal despite its favorable characteristics.
- The proposed Medication Adherence Cascade Tool (MACT) can guide clinicians and patients.
- MACT aims to foster co-production of adherence strategies for optimal therapeutic benefits.
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