Unusual breast findings in a transsexual

A case is reported of the death, following a drug overdose, of a 52-year-old transsexual who had injected paraffin wax into his chest in order to enlarge his breasts many years earlier. This had resulted in subsequent development of chronic abscess and sinus formation. Histological examination showed no evidence of hormone-induced gynecomastia, but instead showed long-standing inflammatory changes with bone formation in the subcutaneous tissue.