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Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination for Paediatric Patients With Inflammatory Bowel Diseases

Gigi Veereman1, Jiri Bronsky2

  • 1Paediatric Gastroenterology Unit, UZ Brussels, VUB, Brussels, Belgium.

Journal of Pediatric Gastroenterology and Nutrition
|August 4, 2021
PubMed

Insights

This review examines evidence on vaccinating pediatric patients with inflammatory bowel diseases (IBD) against SARS-CoV-2. It aims to address parental and adolescent concerns regarding COVID-19 vaccination in IBD management.

Area of Science:

  • Pediatric Gastroenterology
  • Immunology
  • Infectious Diseases

Background:

  • Inflammatory bowel diseases (IBD) affect children and adolescents.
  • Concerns exist regarding the safety and efficacy of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination in this population.
  • The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) IBD working group addresses these concerns.

Purpose of the Study:

  • To review available evidence on SARS-CoV-2 vaccination in pediatric IBD patients.
  • To provide guidance for parents and adolescents regarding COVID-19 vaccination.
  • To consolidate expert opinion on a critical aspect of IBD care during the pandemic.

Main Methods:

  • Systematic review of current scientific literature.
  • Evidence synthesis on vaccine safety and immunogenicity in pediatric IBD.
  • Expert group discussion and consensus building.

Main Results:

  • Evidence supports the safety and efficacy of SARS-CoV-2 vaccines in children and adolescents with IBD.
  • Vaccination is recommended to prevent severe COVID-19 outcomes.
  • No significant increase in IBD flares observed post-vaccination.

Conclusions:

  • COVID-19 vaccination is a crucial component of care for pediatric IBD patients.
  • The benefits of vaccination outweigh potential risks.
  • Continued monitoring and research are essential.

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