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COVID-19 Threat to the World: Current and Possible Diagnostic/Treatment Strategies
Mohd Mughees1, Himanshu Chugh1, Samar Husain Naqvi2
1Department of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi-110062, India.
Insights
Accurate COVID-19 diagnosis and effective treatments are crucial for managing the pandemic. Research is ongoing for better diagnostic tools and cures for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
Area of Science:
- Medical Diagnostics
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic, caused by SARS-CoV-2, presents a global health crisis requiring effective containment strategies.
- Identifying infected individuals through reliable diagnostics is key to preventing viral transmission.
- The urgent need for accessible point-of-care and mass-screening diagnostic methods for SARS-CoV-2 is evident.
Purpose of the Study:
- To review and compile existing diagnostic and treatment techniques for SARS-CoV-2.
- To discuss novel methods for SARS-CoV-2 diagnosis and treatment.
- To highlight the necessity for improved serological tests and effective therapeutics.
Main Methods:
- Literature search on PubMed and Google Scholar (2019-2020) using relevant keywords.
- Compilation and discussion of worldwide diagnostic and treatment strategies for SARS-CoV-2.
- Analysis of current research for potential modifications in diagnosis and treatment.
Main Results:
- Various diagnostic techniques are currently employed for SARS-CoV-2 detection.
- Research is actively pursuing effective treatments and vaccines, with some vaccines already approved.
- No universally effective cure for COVID-19 is yet available.
Conclusions:
- Development of specific serological tests for mass COVID-19 screening is critical.
- There is an ongoing need for affordable, safe, and targeted treatments for SARS-CoV-2.
- Continued research into novel diagnostic and therapeutic approaches is essential to combat the pandemic.
Abstract:
The outbreak of coronavirus disease 2019 (COVID-19) has resulted in a world-wide crisis. To contain the virus, it is important to find infected individuals and isolate them to stop transmission. Various diagnostic techniques are used to check for infection. With the havoc that severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has created, it is imperative to work on alternative diagnostic techniques that can be used at both point of care with little or no expertise and at mass testing (i.e., when screening). Despite extensive research, to this date no specific effective treatment or cure is available to neutralize this viral infection. Globally, researchers are working to develop effective treatments, and several vaccines have been approved for public use. We found the studies that we explored for this review using appropriate key words for indexing in PubMed and Google Scholar from 2019 to 2020. We compile various techniques that have been used worldwide to diagnose and treat SARS-CoV-2 and discuss novel methods that may be modified for use in diagnosis and treatment. It is crucial to develop a more specific serological test for diagnosis that can rule out the possibility of COVID-19 and be used for mass testing. An affordable, safe, targeted, effective treatment must be developed to cure this disease, which has created a public health emergency of international concern.
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