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Updated: Oct 25, 2025

Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion
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Does Walking Help to Generate a Differential Diagnosis?

Malgorzata E Kaminska1,2, Remy M J P Rikers3

  • 1Northern Medical Program, University of Northern British Columbia, Prince George, British Columbia, Canada.

Teaching and Learning in Medicine
|August 5, 2021
PubMed
Summary
This summary is machine-generated.

Walking did not improve the generation of differential diagnoses in medical trainees. The study found no significant increase or decrease in the number or quality of diagnoses when participants walked versus sat.

Keywords:
clinical reasoningdifferential diagnosisexercisemedical education

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Area of Science:

  • Medical Education
  • Cognitive Science
  • Diagnostic Reasoning

Background:

  • Accurate diagnosis is critical in medicine, but challenging with atypical presentations.
  • Diagnostic errors, particularly failure to consider all possibilities, pose risks.
  • Previous research suggests physical activity may enhance cognitive performance.

Purpose of the Study:

  • To investigate if walking enhances differential diagnosis generation in medical trainees.
  • To test the hypothesis that walking increases the number of plausible differential diagnoses.

Main Methods:

  • Medical students and residents generated differential diagnoses from clinical scenarios.
  • Participants completed tasks both sitting and walking on a treadmill.
  • Expert panels evaluated the appropriateness and uniqueness of generated diagnoses.

Main Results:

  • No significant difference was found in the number of total or unique differential diagnoses between sitting and walking conditions.
  • The quality of appropriate unique differential diagnoses also showed no significant change.
  • Exercise (walking) did not impact diagnostic performance in this expert population.

Conclusions:

  • Walking does not appear to enhance or hinder the generation of differential diagnoses in medical trainees with some expertise.
  • The findings suggest that physical activity's impact on diagnostic reasoning may be context-dependent or population-specific.
  • Further research is needed to explore the relationship between physical activity and complex cognitive tasks in medicine.