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Related Concept Videos

Glaucoma: Overview01:25

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

Updated: Oct 25, 2025

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
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SUBHYALOID HEMORRHAGE IN EVANS SYNDROME.

Georges I Guillaume1, Bliss E O'Bryhim1, Surbhi Saini2

  • 1Department of Ophthalmology and Visual Sciences, Washington University in St. Louis, St. Louis, Missouri.

Retinal Cases & Brief Reports
|August 5, 2021
PubMed
Summary

Evans syndrome, a rare autoimmune disorder, can cause sudden vision loss in children due to subhyaloid hemorrhages. Prompt diagnosis and treatment are crucial for vision recovery.

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Last Updated: Oct 25, 2025

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Area of Science:

  • Ophthalmology
  • Hematology
  • Pediatrics

Background:

  • Evans syndrome is a rare autoimmune disorder combining autoimmune hemolytic anemia and immune thrombocytopenia.
  • Ophthalmic manifestations of Evans syndrome are rarely reported, especially in pediatric cases.

Observation:

  • A 15-year-old female presented with acute, painless vision loss in her right eye.
  • Ophthalmic examination revealed bilateral subhyaloid hemorrhages as the cause of vision loss.

Findings:

  • The patient received treatment with intravenous steroids followed by hydroxychloroquine.
  • Resolution of retinal hemorrhages and improvement in vision were observed after treatment.

Implications:

  • Nontraumatic subhyaloid hemorrhage is an uncommon cause of pediatric vision loss.
  • Evans syndrome should be considered in the differential diagnosis of pediatric vision loss with concurrent hematologic abnormalities.