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Updated: Oct 25, 2025

Investigation into Deep Breathing through Measurement of Ventilatory Parameters and Observation of Breathing Patterns
Published on: September 16, 2019
Breathing variability-implications for anaesthesiology and intensive care
Oscar F C van den Bosch1, Ricardo Alvarez-Jimenez2, Harm-Jan de Grooth2
1Departments of Anesthesiology and Intensive Care, Amsterdam UMC, VUMC, ZH 6F 003, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. o.vandenbosch@amsterdamumc.nl.
Breathing variability, or fluctuations in breathing patterns, is influenced by many factors. Low variability may predict mechanical ventilation weaning failure, impacting anesthesia and intensive care.
Area of Science:
- Physiology
- Respiratory Medicine
- Critical Care Medicine
Background:
- The respiratory system exhibits dynamic adaptability to internal and external stimuli, leading to variations in breathing parameters like rate and volume.
- Breathing variability is affected by physiological states (e.g., sleep) and pathological conditions (e.g., pulmonary diseases, hypoxia, anxiety).
Purpose of the Study:
- To review methods for quantifying breathing variability.
- To summarize factors influencing breathing variability.
- To discuss the clinical implications of breathing variability in anesthesia and intensive care.
Main Methods:
- Literature review of studies on breathing variability quantification.
- Synthesis of research on conditions affecting breathing patterns.
- Analysis of the role of breathing variability in clinical settings.
Main Results:
- Breathing variability is a measurable physiological parameter influenced by diverse factors.
- Low respiratory variability has been linked to increased likelihood of weaning failure from mechanical ventilation.
- Understanding breathing variability is crucial for managing patients in critical care.
Conclusions:
- Breathing variability assessment offers insights into respiratory system function.
- Abnormal breathing variability may serve as a biomarker for specific clinical outcomes.
- Further research into breathing variability can optimize anesthetic and intensive care practices.
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