Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

192
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
192
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

262
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
262
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

261
Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
261
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy01:16

Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

663
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
663
Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

182
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
182
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

860
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
860

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In sphincter of Oddi patients, amelioration of pain is primarily associated with common bile duct dilation rather than hepatobiliary scintigraphy excretion time or alanine amino transferase - a single centre, retrospective study.

Clinical physiology and functional imaging·2026
Same author

The effect of ghrelin on insulin sensitivity and beta-cell function after sleeve gastrectomy.

American journal of physiology. Endocrinology and metabolism·2026
Same author

[Late sequelae after gastrointestinal surgery in adults].

Ugeskrift for laeger·2026
Same author

Perioperative antibiotics for mild or moderate acute cholecystitis - A systematic review and meta-analysis.

American journal of surgery·2026
Same author

Laparoscopic bariatric surgery versus any non-surgical intervention for adolescents or adults with obesity: protocol for a systematic review with meta-analysis and trial sequential analysis of randomised clinical trials.

BMJ open·2026
Same author

Effects of Acute Iso- and Hypocaloric Carbohydrate Restriction on Liver Fat and Glucose and Lipid Metabolism.

The Journal of clinical endocrinology and metabolism·2025

Related Experiment Video

Updated: Oct 25, 2025

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
06:19

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis

Published on: May 16, 2025

527

[Acute diverticulitis can be treated without antibiotics].

Marie-Louise Dichman1, Daniel Mønsted Shabanzadeh

  • 1mldichman@gmail.com.

Ugeskrift for Laeger
|August 6, 2021
PubMed
Summary

Antibiotics do not improve outcomes for uncomplicated acute diverticulitis (inflammation of pouches in the colon). Evidence from three trials suggests they do not prevent complications or the need for surgery.

Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Clinical Medicine

Background:

  • Diverticulitis, a complication of diverticulosis, has traditionally been managed with antibiotics.
  • Emerging evidence suggests diverticulitis may be an inflammatory rather than infectious process.
  • Risk factors associated with diverticulitis support an inflammatory etiology.

Purpose of the Study:

  • To review the current evidence regarding the efficacy of antibiotic treatment for uncomplicated acute diverticulitis.
  • To evaluate the impact of antibiotics on key clinical outcomes in diverticulitis management.
  • To determine the necessity of antibiotics in treating uncomplicated acute diverticulitis.

Main Methods:

  • Systematic review of relevant medical literature.

More Related Videos

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

27.4K
Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
03:42

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis

Published on: March 15, 2024

802

Related Experiment Videos

Last Updated: Oct 25, 2025

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
06:19

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis

Published on: May 16, 2025

527
Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

27.4K
Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
03:42

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis

Published on: March 15, 2024

802
  • Analysis of three randomized clinical trials (RCTs) investigating antibiotic use.
  • Evaluation of outcomes including complications, emergency surgery, recurrence, and long-term sequelae.

    • Main Results:

    • Antibiotic therapy showed no significant effect on the incidence of complications.
    • No demonstrable benefit of antibiotics regarding emergency surgery rates.
    • Antibiotics did not influence recurrence rates or the need for elective colonic resections.
    • Long-term complications were not found to be reduced by antibiotic treatment.

    Conclusions:

    • Current evidence does not support the routine use of antibiotics for uncomplicated acute diverticulitis.
    • Antibiotic treatment appears to offer no advantage over non-antibiotic management for this condition.
    • Further research and clinical guidelines should consider these findings to optimize diverticulitis treatment.