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Study Protocol: The Evaluation Study for Social Cognition Measures in Japan (ESCoM).

Ryotaro Kubota¹, Ryo Okubo^1,2, Hisashi Akiyama³

¹Department of Psychiatry, National Center of Neurology and Psychiatry Hospital, Tokyo 187-8551, Japan.

Journal of Personalized Medicine

|August 6, 2021

Summary

This study evaluates social cognition measures for schizophrenia patients in Japan, aiming to improve social functioning assessments. Findings will validate tools and explore factors influencing social cognition in this population.

Keywords:

developmental disorders facial expression recognition mental disorders quality of life schizophrenia social cognition social functioning test battery

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Area of Science:

Psychiatry
Neuroscience
Psychometrics

Background:

Social cognitive impairment significantly hinders social participation in schizophrenia.
Limited availability of validated social cognition measures in Japan restricts research and clinical application.
The Evaluation Study for Social Cognition Measures in Japan (ESCoM) aims to address this gap.

Purpose of the Study:

To confirm the psychometric characteristics of social cognition measures in a Japanese context.
To promote research on social cognition in schizophrenia.
To identify predictors of social functioning and determinants of social cognition.

Main Methods:

Cross-sectional observational study involving 140 schizophrenia patients and 70 healthy controls from three Japanese facilities.
Primary analysis: calculating psychometric indicators to assess predictive validity for social functioning.
Secondary analyses: evaluating reliability and validity of Japanese translations, exploring determinants like patient background, symptoms, defeatist beliefs, and gut microbiota.

Main Results:

Psychometric indicators will be calculated to determine their ability to independently predict social functioning.
Reliability and validity of Japanese-translated social cognition measures will be assessed.
Exploratory analysis will investigate patient background, psychiatric symptoms, defeatist performance beliefs, and gut microbiota as potential determinants of social cognition.

Conclusions:

This study will provide validated social cognition measures for use in Japan, facilitating research and clinical practice.
Understanding the predictors of social functioning and determinants of social cognition is crucial for developing targeted interventions.
The findings will contribute to improving social participation for individuals with schizophrenia.