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Related Experiment Videos

Viruses and diarrhea--a review.

M C Steinhoff

    American Journal of Diseases of Children (1960)
    |March 1, 1978
    PubMed
    Summary

    Few viruses cause acute gastroenteritis, with rotavirus common in children and parvovirus-like agents causing epidemics. However, 30% of cases remain unexplained, requiring further research into viral gastroenteritis pathogenesis.

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    Vaccine·2006

    Area of Science:

    • Virology
    • Infectious Diseases
    • Gastroenterology

    Background:

    • Acute gastroenteritis is a significant global health concern, particularly in children.
    • Identifying causative viral agents is crucial for effective prevention and treatment strategies.
    • Current literature reveals a limited number of definitively identified viral pathogens responsible for acute gastroenteritis.

    Observation:

    • A literature review reveals limited confirmed viral causes for acute gastroenteritis.
    • Rotavirus (family Reoviridae) is a primary cause of gastroenteritis in children.
    • Parvovirus-like agents, including Norwalk, Hawaii, MC, and W, are implicated in epidemic gastroenteritis.

    Findings:

    • Established viral agents account for the majority of identified gastroenteritis cases.
    • Marcy, FS, and Niigata agents are strongly suspected in specific gastroenteritis outbreaks.
    • A substantial proportion (30%) of acute gastroenteritis cases remain etiologically uncharacterized.

    Implications:

    • Further research is needed to identify the viral agents responsible for the remaining 30% of gastroenteritis cases.
    • Understanding the pathogenesis and immunology of viral gastroenteritides is essential for developing targeted interventions.
    • Enhanced etiological identification will improve disease surveillance and outbreak response efforts.

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