Related Experiment Video

Updated: Oct 25, 2025

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
04:36

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Published on: January 12, 2024

1.3K

The Association of Diabetic Retinopathy and Cardiovascular Disease: A 13-Year Nationwide Population-Based Cohort

Chin-Yuan Hsu1, Chee-Ming Lee2,3, Kuan-Yu Chou2,3

  • 1Department of Health Policy and Management, Chung Shan Medical University, Taichung 40201, Taiwan.

International Journal of Environmental Research and Public Health
|August 7, 2021
PubMed

Insights

Patients with diabetic retinopathy (DR) face a significantly higher risk of cardiovascular disease (CVD). Early detection and monitoring of DR in diabetes mellitus (DM) patients are crucial for managing CVD risk.

Area of Science:

  • Ophthalmology
  • Cardiology
  • Endocrinology

Background:

  • Diabetic retinopathy (DR) is associated with increased cardiovascular disease (CVD) risk factors.
  • A hypothesis suggests a higher relative risk of CVD in patients with more severe DR.

Purpose of the Study:

  • To investigate the association between DR and CVD.
  • To evaluate the incidence and risk of CVD in patients with DR.

Main Methods:

  • Utilized the National Health Insurance Research Database (NHIRD) in Taiwan.
  • Conducted a nationwide population-based retrospective cohort study from 2001 to 2013.
  • Analyzed CVD incidence in patients with DR over a 13-year follow-up period.

Main Results:

  • CVD incidence rates were 2.026 times higher in diabetes mellitus (DM) without DR compared to the Non-DM group.
  • CVD incidence rates were 2.75 times higher in DM with DR compared to the Non-DM group.
  • The relative risk of CVD was elevated in DR patients compared to the Non-DM group for both sexes.

Conclusions:

  • DR is linked to a significantly increased risk of CVD.
  • Close monitoring of DM patients, particularly those with co-existing DR, is essential for cardiovascular health.
  • Clinical care strategies should prioritize managing CVD risk in the DR population.
Abstract

Keywords:
cardiovascular diseasediabetic retinopathynationwide population-based epidemiological study

More Related Videos

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats07:41

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

6.2K
Quantification of Diabetes-induced Adherent Leukocytes in Retinal Vasculature05:54

Quantification of Diabetes-induced Adherent Leukocytes in Retinal Vasculature

Published on: January 24, 2025

452

Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
85
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
3.5K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
2.2K
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
537
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
113
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
1.3K