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Retrograde Revascularization of Tibial Arteries in Patients with Critical Limb Ischemia: Plantar-Arch Versus
Erik Stahlberg1, Andreas Stroth1, Alexander Haenel1
1Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
Insights
The transpedal-access approach for below-the-knee (BTK) revascularization showed higher procedural success compared to the plantar-arch approach. Calcifications impacted success in the plantar-arch method, but outcomes were similar for limb salvage and survival.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Therapy
Background:
- Critical limb ischemia (CLI) poses a significant challenge, often requiring below-the-knee (BTK) revascularization.
- Antegrade approaches can fail, necessitating alternative retrograde strategies for BTK artery revascularization.
Purpose of the Study:
- To compare the efficacy and safety of retrograde plantar-arch versus transpedal-access approaches for BTK revascularization.
- To evaluate the impact of calcification on procedural success in these retrograde techniques.
Main Methods:
- Retrospective analysis of 811 patients undergoing BTK revascularization, focusing on 115 with prior failed antegrade attempts.
- Patients were divided into plantar-arch (PLANTAR) and transpedal-access (TRANSPEDAL) retrograde groups.
- Endpoints included technical success, procedural success, complications, limb salvage, and survival, with analysis of calcification's influence.
Main Results:
- Procedural success was significantly higher in the TRANSPEDAL group (52%) compared to the PLANTAR group (34%) (p=0.04).
- Calcification at the pedal-plantar loop and tibial target lesion significantly hindered technical and procedural success in the PLANTAR group.
- No significant differences were observed in technical success, complications, limb salvage, or survival between the two retrograde approaches.
Conclusions:
- The transpedal-access approach offers a higher procedural success rate for BTK revascularization after failed antegrade attempts.
- Calcification is a critical factor for failure in the plantar-arch retrograde approach.
- Both retrograde techniques demonstrate comparable feasibility, safety, and long-term limb salvage and survival rates.
Purpose:
To compare retrograde plantar-arch and transpedal-access approach for revascularization of below-the-knee (BTK) arteries in patients with critical limb ischemia (CLI) after a failed antegrade approach.
Materials And Methods:
Retrospectively we identified 811 patients who underwent BTK revascularization between 1/2014 and 1/2020. In 115/811 patients (14.2%), antegrade revascularization of at least 1 tibial artery had failed. In 67/115 (58.3%), patients retrograde access to the target vessel was achieved via the femoral access and the plantar-arch (PLANTAR-group); and in 48/115 patients (41.7%) retrograde revascularization was performed by an additional retrograde puncture (TRANSPEDAL-group). Comorbidities, presence of calcification at pedal-plantar-loop/transpedal-access-site, and tibial-target-lesion was recorded. Endpoints were technical success (PLANTAR-group: crossing the plantar-arch; TRANSPEDAL-group: intravascular placement of the pedal access sheath), procedural success [residual stenosis <30% after plain old balloon angioplasty (POBA)], and procedural complications limb salvage and survival. Correlations between calcification at access site/tibial-target-lesion and technical/procedural-success were tested.
Results:
Technical success was achieved in 50/67 (75%) patients of the PLANTAR-group and in 39/48 (81%) patients of the TRANSPEDAL-group (p=0.1). Procedural success was obtained in 23/67 (34%) patients of the PLANTAR-group and in 25/48 (52%) patients of the TRANSPEDAL-group (p=0.04). In 14/49 (29%) cases with calcification at the pedal-plantar loop, technical success was not achieved (p=0.04), and in 33/44 (75%) patients with calcification at the tibial-target-lesion, procedural success was not attained (PLANTAR-group) (p=0.026). In the TRANSPEDAL-group, correlations between calcification at access site/tibial-target-lesion and technical/procedural-success were not observed (p=0.2/p=0.4). In the PLANTAR-group, minor complications occurred in 13/67 (19%) and in the TRANSPEDAL-group in 4/48 patients (8%) (p=0.08). Limb salvage at 12 (18) months was 90% (82%) (PLANTAR-group; 95%CI 15.771-18.061) and 84% (76%) (TRANSPEDAL-group; 95%CI 14.475-17.823) (Log-rank p=0.46). Survival at 12 (18) months was 94% (86%) (PLANTAR-group; 95%CI 16.642-18.337) and 85% (77%) (TRANSPEDAL; 95%CI 14.296-17.621) (Log-rank p=0.098).
Conclusion:
Procedural success was significantly higher using the transpedal-access approach. Calcifications at pedal-plantar loop and target-lesion significantly influenced technical/procedural failure using the plantar-arch approach. No significant difference between both retrograde techniques in terms of feasibility, safety, and limb salvage/survival was found.
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