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Non-static framework for understanding adaptive designs: an ethical justification in paediatric trials

Michael Os Afolabi1, Lauren E Kelly2,3,4

  • 1Department of Pediatrics and Child Health, Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada michael.afolabi@umanitoba.ca curiousmaikl@yahoo.com.

Journal of Medical Ethics
|August 7, 2021
PubMed
Summary

Paediatric adaptive designs (PADs) offer efficient and ethical drug evaluation for children. These trials enhance safety and scientific value, though stakeholder collaboration is needed to clarify regulatory aspects.

Keywords:
childrenclinical trialsethicspaediatricsresearch on special populations

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