[Research Progress of Biodegradable Vascular Stent].

Area of Science:

• Biomaterials Science
• Cardiovascular Medicine
• Medical Device Engineering

Background:

• Biodegradable vascular stents present improved biocompatibility compared to traditional drug-eluting stents.
• Their transient presence in the body eliminates the need for long-term anti-rejection medications.
• This makes them a promising focus for coronary heart disease treatment.

Purpose of the Study:

• To review the historical development of biodegradable vascular stents.
• To analyze the current research status of various biodegradable stent materials in vivo.
• To identify existing challenges and predict future research trajectories.

Main Methods:

• Literature review of biodegradable stent development.
• Analysis of in vivo studies on different biodegradable stent materials (animal and human).
• Identification of current limitations and future research trends.

Main Results:

• Biodegradable stents demonstrate enhanced biocompatibility and physiological integration.
• Degradation allows natural vessel rebuilding after function restoration.
• Current research highlights material-specific challenges and performance variations.

Conclusions:

• Biodegradable vascular stents are a significant advancement in cardiovascular treatment.
• Further research is needed to overcome existing material and performance challenges.
• Future directions include optimizing degradation profiles and long-term efficacy.