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Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
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Pigmentation

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Mutations

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Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Connective Tissue Cell Types

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Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
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Vitamin D: Do We Need More Than Sunshine?

Sneha Baxi Srivastava1

  • 1Department of Pharmacy Practice, Rosalind Franklin University of Medicine and Science, College of Pharmacy, North Chicago, Illinois, and Lake County Health Department, Waukegan, Illinois.

American Journal of Lifestyle Medicine
|August 9, 2021
PubMed
Summary

Vitamin D plays a crucial role in health, but optimal levels and supplementation strategies remain debated. This review clarifies vitamin D

Area of Science:

  • Endocrinology
  • Nutritional Science
  • Public Health

Background:

  • Vitamin D is essential for numerous physiological processes.
  • Widespread discussion and research surround vitamin D's health implications.
  • Controversy exists regarding optimal serum levels and sufficiency metrics.

Purpose of the Study:

  • To elucidate the multifaceted role of vitamin D in human health.
  • To critically review existing scientific evidence on vitamin D.
  • To provide current recommendations for vitamin D supplementation.

Main Methods:

  • Literature review of scientific studies on vitamin D.
  • Analysis of evidence regarding vitamin D's functions and deficiencies.
  • Evaluation of current supplementation guidelines.
Keywords:
cholecalciferolergocalciferolvitamin D

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Main Results:

  • The article details vitamin D's physiological functions.
  • Evidence on the consequences of vitamin D insufficiency is presented.
  • Current recommendations for supplementation are outlined.

Conclusions:

  • The role of vitamin D is complex and warrants further investigation.
  • Current recommendations suggest a need for more than just sun exposure for adequate vitamin D levels.
  • Further research is needed to definitively establish optimal vitamin D status and supplementation protocols.