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Related Experiment Videos

Hyperhydration with glycerol solutions.

M L Riedesel1, D Y Allen, G T Peake

  • 1Department of Biology, University of New Mexico, Albuquerque 87131.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|December 1, 1987
PubMed
Summary
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Glycerol combined with excess fluid intake effectively promotes hyperhydration in both males and females. This method reduces urine volume and increases plasma osmolality for up to four hours.

Area of Science:

  • Physiology
  • Sports Science
  • Nutrition

Background:

  • Hyperhydration is crucial for endurance athletes to improve performance and thermoregulation.
  • Glycerol is a potential hyperhydration agent due to its osmotic properties.
  • Understanding optimal glycerol dosage and fluid intake protocols is essential.

Purpose of the Study:

  • To investigate the efficacy of glycerol as a hyperhydration agent.
  • To determine the effects of different glycerol dosages and fluid intake timings on hydration status.
  • To assess physiological markers of hydration in response to glycerol and fluid consumption.

Main Methods:

  • Two experimental series involving male and female subjects ingesting varying doses of glycerol (0.5-1.5 g/kg) and saline solution.

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  • Measurements included plasma osmolality, hemoglobin, hematocrit, and urine volume over a 4-hour period.
  • Each subject served as their own control to minimize inter-individual variability.

    • Main Results:

    • Glycerol ingestion led to increased plasma osmolality for up to 2 hours.
    • Total urine volume was significantly reduced over the 4-hour experimental duration.
    • No significant changes in hemoglobin or hematocrit were observed, indicating no hemoconcentration.

    Conclusions:

    • Glycerol combined with adequate fluid intake is an effective strategy for inducing hyperhydration.
    • This hyperhydration state can be maintained for at least 4 hours.
    • Glycerol shows promise as a safe and effective ergogenic aid for athletes.