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Published on: September 2, 2021
Purulent Pericarditis: Is It Really a Disease of the Past?
Laura Costa1, Diana Carvalho2, Elisabete Coelho1
1Unidade de Cuidados Intensivos Polivalente, Hospital de Braga, Braga, Portugal.
Abstract:
The authors present a case of purulent pericarditis probably secondary to respiratory infection, a rare entity in the antibiotic era. Pericardial fluid analysis identified streptococci and oral anaerobes as the causative agents. A prolonged and complicated diagnostic and therapeutic course, which included a long stay in the intensive care unit, is described, and a review of purulent pericarditis provided. Pericardial effusion, particularly in the setting of concomitant respiratory infection and immunocompromise or other risk factors, should raise the suspicion of bacterial pericarditis and prompt its timely diagnosis and treatment. Purulent pericarditis can be lethal and has potentially severe complications, so adequate antimicrobial therapy and source control are key.
Learning Points:
Purulent pericarditis is a rare infection, mostly resulting from contiguous or haematogenous spread, with diagnosis often delayed because signs and symptoms are unspecific.Treatment must include drainage of the pericardial space, combined with systemic antibiotics.Prognosis is variable, depending largely on the speed of diagnosis and treatment, as death is almost certain without adequate source control.
Insights
Purulent pericarditis, a rare bacterial infection, can arise from respiratory infections. Prompt diagnosis and treatment, including antibiotics and drainage, are crucial for survival and preventing severe complications.
Area of Science:
- Infectious Diseases
- Cardiology
Background:
- Purulent pericarditis is a rare but serious condition, often secondary to other infections.
- Its incidence has decreased in the antibiotic era but remains a significant threat, especially in immunocompromised individuals or those with risk factors.
Purpose of the Study:
- To present a case of purulent pericarditis secondary to respiratory infection.
- To review the diagnosis, treatment, and prognosis of this rare entity.
- To emphasize the importance of early recognition and intervention.
Main Methods:
- Case report detailing a prolonged diagnostic and therapeutic course.
- Analysis of pericardial fluid to identify causative agents (Streptococci and oral anaerobes).
- Literature review on purulent pericarditis.
Main Results:
- Identified Streptococci and oral anaerobes as causative agents in the presented case.
- Highlighted the challenges in diagnosis due to unspecific signs and symptoms.
- Described a complicated clinical course requiring intensive care unit admission.
Conclusions:
- Pericardial effusion, especially with respiratory infection or risk factors, warrants suspicion for bacterial pericarditis.
- Timely diagnosis and treatment, including pericardial drainage and systemic antibiotics, are critical.
- Adequate source control and rapid intervention significantly impact patient prognosis, as untreated cases can be lethal.
Related Concept Videos
Pericarditis I: Introduction
Pericarditis II: Clinical Features and Diagnostic Tests
Pericarditis III: Medical Management
Pericarditis IV: Nursing Management
Rheumatic Heart Disease I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis

