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COVID-19 presenting as persistent hiccups: a case report.

Diogo Ribeiro de Sene1, Diego Moreno Watashi2, Isabella de Oliveira Bilitardo1

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Summary

Persistent hiccups can be an early symptom of COVID-19. A young man with flu-like symptoms experienced prolonged hiccups, which resolved after COVID-19 treatment.

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Area of Science:

  • Medicine
  • Pulmonology
  • Infectious Diseases

Background:

  • Hiccups are involuntary spasmodic contractions of the diaphragm and intercostal muscles.
  • They are classified as acute (<48 hours), persistent (48 hours to 1 month), or intractable (>1 month).
  • Persistent hiccups can indicate underlying medical conditions.

Observation:

  • A previously healthy 29-year-old man presented with flu-like symptoms and a two-day history of persistent hiccups.
  • Physical examination and vital signs were normal.
  • A chest CT scan revealed scattered ground-glass opacities.

Findings:

  • The patient tested positive for COVID-19.
  • Chlorpromazine was administered for hiccups, leading to improvement within 10 hours.
  • The patient was discharged without hiccups or complications.

Implications:

  • This case highlights persistent hiccups as a potential early, and sometimes sole, presenting symptom of COVID-19.
  • It suggests that COVID-19 should be considered in the differential diagnosis of new-onset persistent hiccups.
  • Prompt diagnosis and management of COVID-19 can effectively resolve associated symptoms like hiccups.