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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

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Decrease in intravenous thrombolysis and poor short-term functional prognosis for acute ischemic stroke during the

Xueqian Xu1, Yuenan Xiao2, Jia Li1

  • 1Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang Province, China.

Journal of Neurology
|August 11, 2021
PubMed

Insights

The COVID-19 pandemic reduced acute ischemic stroke (AIS) patients receiving intravenous thrombolysis (IVT) and lengthened treatment times. This led to worse short-term prognoses for AIS patients during the pandemic.

Area of Science:

  • Neurology
  • Public Health
  • Emergency Medicine

Background:

  • The COVID-19 pandemic significantly impacted global healthcare systems.
  • Neurology departments faced challenges in managing acute ischemic stroke (AIS) patients.

Purpose of the Study:

  • To compare the impact of the COVID-19 pandemic on intravenous thrombolysis (IVT) treatment for AIS patients.
  • To analyze changes in patient attendance and short-term prognosis from 2019 to 2020.

Main Methods:

  • Retrospective analysis of AIS patients receiving IVT between 2019 and 2020.
  • Comparison of demographic data, door-to-needle time (DNT), and neurological scores (NIHSS).
  • Statistical analysis of discharged modified Rankin Scale (mRS) and NIHSS scores.

Main Results:

  • A 24.7% reduction in IVT admissions was observed in 2020 compared to 2019.
  • Door-to-needle time (DNT) significantly increased in 2020 (51.60 ± 23.80 min) versus 2019 (46.80 ± 21.90 min).
  • A higher proportion of AIS patients had poor short-term functional prognosis (mRS) in 2020 (38.2%) compared to 2019 (29.2%).

Conclusions:

  • The COVID-19 pandemic led to decreased AIS admissions and prolonged "green channel" times for stroke treatment.
  • Worsened short-term prognoses for AIS patients were associated with pandemic-related disruptions.
  • Maintaining effective stroke pathways and adequate resources is crucial during pandemics to mitigate patient harm.
Abstract

Keywords:
Acute ischemic strokeCOVID-19Door to needle timeFunctional prognosisIntravenous thrombolysis

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