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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

899
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Iris Fixation via External Pentagram Suturing
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[Secondary Angle Closure Glaucoma].

Simone Nüßle, Jan Lübke

    Klinische Monatsblatter Fur Augenheilkunde
    |August 11, 2021
    PubMed
    Summary
    This summary is machine-generated.

    Secondary angle closure glaucoma, a complex eye condition, involves various causes blocking fluid flow. Understanding these distinct mechanisms is key to effective treatment and managing intraocular pressure.

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    Area of Science:

    • Ophthalmology
    • Glaucoma Research
    • Ocular Fluid Dynamics

    Background:

    • Secondary angle closure glaucoma (SACG) is a heterogeneous condition.
    • It arises from diverse mechanisms obstructing aqueous humor flow.
    • SACG presents significant therapeutic challenges.

    Purpose of the Study:

    • To provide an overview of SACG causes, diagnostics, and therapies.
    • To categorize SACG into pupillary block, pulling, and pushing mechanisms.
    • To highlight the importance of treating underlying causes.

    Main Methods:

    • Review of literature on secondary angle closure glaucoma.
    • Categorization of causes based on obstruction mechanism (pupillary block, pulling, pushing).
    • Discussion of diagnostic approaches and targeted therapies for exemplary causes.

    Main Results:

    • Identified mechanical causes (iris bombé, air/oil), 'pulling' causes (neovascularization, inflammation, ICE syndrome), and 'pushing' causes (gas tamponade, neoplasms, aqueous misdirection).
    • Emphasized that treatment must prioritize the underlying cause.
    • Surgical interventions for intraocular pressure reduction have limited success in many SACG forms.

    Conclusions:

    • Effective management of SACG requires precise diagnosis of its specific subgroup.
    • Tailored therapy addressing the etiological mechanism is crucial.
    • Knowledge of SACG subgroups and their pathogenesis guides optimal treatment selection.