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Related Experiment Video

Updated: Oct 24, 2025

A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging

A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging

Published on: March 17, 2023

NIR-II Organic Nanotheranostics for Precision Oncotherapy.

Hanming Dai¹, Xiaorui Wang¹, Jinjun Shao¹

¹Key Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), Nanjing, 211816, China.

Small (Weinheim an Der Bergstrasse, Germany)

|August 12, 2021

Summary

Organic nanotheranostics offer a promising approach for precision oncotherapy, integrating tumor diagnosis and treatment. These advanced materials show great potential for safer and more effective cancer care.

Keywords:

organic nanotheranostics precision oncotherapy second near-infrared

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Area of Science:

Biomedical Engineering
Nanotechnology
Oncology

Background:

Precision oncotherapy aims to eliminate tumors with minimal damage to healthy tissues.
Second near-infrared (NIR-II) nanotheranostics offer combined diagnostic and therapeutic capabilities on a single platform for precise tumor treatment.
NIR-II organic nanotheranostics are favored over inorganic counterparts due to superior biocompatibility, reproducibility, excretion, and biosafety.

Purpose of the Study:

To systematically review recent advancements in NIR-II organic nanotheranostics for integrated tumor diagnosis and therapy.
To analyze the theranostic modes and performance of these nanoplatforms.
To identify current challenges and future directions for NIR-II organic nanotheranostics in precision oncotherapy.

Main Methods:

Literature review of recent progress in NIR-II organic nanotheranostics.
Analysis of theranostic strategies and their efficacy.
Discussion of current limitations and future research opportunities.

Main Results:

NIR-II organic nanotheranostics demonstrate significant potential for simultaneous tumor diagnosis and treatment.
These nanoplatforms offer advantages in biocompatibility and safety compared to inorganic alternatives.
The review highlights various theranostic modes and their performance in preclinical settings.

Conclusions:

NIR-II organic nanotheranostics represent a promising avenue for advancing precision oncotherapy.
Further research is needed to address current challenges and optimize these systems for clinical translation.
Continued development is crucial for realizing the full potential of these nanotheranostics in cancer treatment.