Related Experiment Video
Updated: Oct 24, 2025
03:43
Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
Published on: July 11, 2025
260
Adverse Events Associated with Routine Colonoscopy in Patients with End-Stage Renal Disease
Hyeon Jeong Goong1, Bong Min Ko2, Moon Sung Lee1
1Department of Internal Medicine, Digestive Disease Center and Research Institute, Soonchunhyang University School of Medicine, Soonchunhyang University Bucheon Hospital, 170 Jomaru-ro, Wonmi-gu, Bucheon, 420-767, Republic of Korea.
Digestive Diseases and Sciences
|August 12, 2021
Summary
Routine colonoscopy is generally safe for patients with end-stage renal disease (ESRD) on dialysis, though adverse events are more common than in healthy adults. Careful consideration is advised for older hemodialysis patients.
Area of Science:
- Nephrology
- Gastroenterology
- Clinical Medicine
Background:
- Limited data exists on the safety of routine colonoscopy in end-stage renal disease (ESRD) patients, including bowel preparation and sedation.
- Colonoscopy is frequently performed in ESRD patients, necessitating an understanding of associated risks.
Purpose of the Study:
- To investigate the safety of colonoscopy in patients with ESRD undergoing peritoneal dialysis (PD) or hemodialysis (HD).
- To compare the incidence of adverse events (AEs) in ESRD patients versus a healthy control group.
Main Methods:
- Retrospective review of 538 ESRD patients who underwent colonoscopy (2010-2020).
- Propensity score-matched comparison with healthy adults to analyze cardiovascular/pulmonary and procedure-related AEs.
- Comparison of AE rates between PD and HD groups.
Main Results:
- Overall AE rate in ESRD patients was 5.7%, significantly higher than healthy adults (0.6%).
- All AEs were cardiovascular/pulmonary; no perforations or bleeding occurred. Most AEs were mild.
- AE incidence was higher in hemodialysis (HD) than peritoneal dialysis (PD) patients (6.1% vs. 3.5%), but not statistically significant.
Conclusions:
- Colonoscopy-related AEs in ESRD patients on dialysis are more frequent than in healthy individuals but are typically not severe.
- Routine colonoscopy can be safely performed in ESRD patients, irrespective of dialysis modality.
- Increased caution is recommended for older ESRD patients undergoing hemodialysis.
Related Concept Videos
01:25Endoscopic Procedures II: Colonoscopy
271
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
271
01:28Cardiac Catheterization I: Pre-Procedure Overview
312
Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
312
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
101
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
101
01:24Hemodialysis II: Procedure and Complications
203
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
203
01:19Imaging Studies VII: Vascular Imaging
100
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
100
01:25Chronic Kidney Disease I: Introduction
282
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
282