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Updated: Oct 24, 2025

Study of Experimental Organ Donation Models for Lung Transplantation
Published on: March 15, 2024
[... because We Should not Forget! Neonatal Organ Donation]
Christof Dame1, Kerstin von der Hude1, Markus Kliemann2
1Klinik für Neonatologie, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.
Organ donation after brain death in newborns is rare but possible. This case demonstrates successful heart transplantation from a neonate, highlighting legal and medical considerations.
Area of Science:
- Neonatology
- Transplantation Medicine
- Pediatric Critical Care
Background:
- Neonatal deaths account for nearly 40% of pediatric fatalities.
- Organ donation in neonates is infrequent despite this statistic.
- Perinatal asphyxia can lead to irreversible loss of brain function in newborns.
Purpose of the Study:
- To report a case of successful heart transplantation from a neonate.
- To discuss the legal and medical challenges in neonatal organ donation.
- To highlight the nursing perspective in such complex cases.
Main Methods:
- Diagnosis of irreversible loss of brain function in a neonate according to German transplantation law.
- Organ procurement following established guidelines for brain death confirmation.
- Successful heart retrieval and transplantation.
Main Results:
- A neonate diagnosed with irreversible loss of brain function following perinatal asphyxia underwent heart donation.
- The heart was successfully transplanted.
- Legal challenges included anonymous birth, guardianship, and deceased welfare rights.
- Medical focus was on neonatal brain death diagnostics and organ preservation.
- Nursing care differed significantly from palliative care scenarios.
Conclusions:
- Successful organ donation and transplantation are feasible in neonates with irreversible loss of brain function.
- Addressing legal complexities and specialized medical protocols is crucial.
- Involving all stakeholders in decision-making is vital for emotional support.
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09:54Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
07:49Large-Animal Model of Donation after Circulatory Death and Normothermic Regional Perfusion for Cardiac Assessment
Published on: May 10, 2022
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