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Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
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Open Globe Injury with Intraocular Foreign Body
Filippos Vingopoulos1, Yvonne Wang2, Seanna Grob2,3
1Harvard Retinal Imaging Lab, Massachusetts Eye and Ear, Boston MA.
Journal of Vitreoretinal Diseases
|August 13, 2021
Summary
Open globe injuries with intra-ocular foreign bodies in the posterior segment lead to worse visual outcomes and more complications. Early repair is crucial for better results in these traumatic eye injuries.
Area of Science:
- Ophthalmology
- Trauma Surgery
- Ocular Trauma
Background:
- Open globe injuries (OGI) with intra-ocular foreign bodies (IOFB) are severe ocular emergencies.
- Understanding the characteristics and outcomes of OGI with IOFB is crucial for effective management.
Purpose of the Study:
- To investigate the characteristics of open globe injuries (OGI) with intra-ocular foreign bodies (IOFB).
- To analyze long-term visual outcomes, complications, and subsequent surgery rates for OGI with IOFB.
Main Methods:
- Retrospective case series of 57 patients with OGI and IOFB from 2010-2015.
- Data collected: time to repair, injury/IOFB location, retinal detachment (RD) rate, visual acuity (VA), and need for surgery.
Main Results:
- 66.7% achieved final vision of 20/40 or better; 75.4% achieved 20/150 or better.
- Posterior segment IOFB was associated with higher RD rates (58.3% vs 9.1%), increased vitrectomy rates, and worse visual prognosis (p=0.014).
- No cases of endophthalmitis were reported.
Conclusions:
- Posterior segment IOFB in OGI significantly increases complication and re-operation rates.
- OGI with posterior IOFB have a worse visual prognosis compared to anterior segment IOFB.
- Prompt management of OGI with IOFB is essential to improve patient outcomes.
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