How cells respond and adapt to heat stress through alterations in gene expression

Hsp90 chaperone control over transcriptional regulation by the yeast Slt2(Mpk1)p and human ERK5 mitogen-activated protein kinases (MAPKs).

Biochemical Society transactions·2006

The Hsp90 chaperone as a promising drug target.

Current opinion in investigational drugs (London, England : 2000)·2002

The ZbYME2 gene from the food spoilage yeast Zygosaccharomyces bailii confers not only YME2 functions in Saccharomyces cerevisiae, but also the capacity for catabolism of sorbate and benzoate, two major weak organic acid preservatives.

Molecular microbiology·2001

Increasing Saccharomyces cerevisiae stress resistance, through the overactivation of the heat shock response resulting from defects in the Hsp90 chaperone, does not extend replicative life span but can be associated with slower chronological ageing of nondividing cells.

Molecular genetics and genomics : MGG·2001

Chronological lifespan of stationary phase yeast cells; a model for investigating the factors that might influence the ageing of postmitotic tissues in higher organisms.

Yeast (Chichester, England)·2001

The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains.

The EMBO journal·2000

Involvement of NOD1/NF-κB/MAPK pathway in the protective effect of procyanidin B2 against methotrexate-induced nephrotoxicity.

Science progress·2026

Documented arteriovenous fistula thrill category and Doppler hemodynamics in mature radiocephalic fistulas: A single-center retrospective study.

Science progress·2026

Diagnostic performance of Node-RADS in assessing regional lymph node metastasis and prognosis in resected gastric cancer.

Science progress·2026

Coats disease: A narrative review of clinical spectrum, imaging features, and contemporary management.

Science progress·2026

First-24-hour aspirin exposure and 28-day mortality in critically ill adults with cerebral embolism: A retrospective MIMIC-IV cohort study.

Science progress·2026

Structural white matter alterations in borderline personality disorder: A narrative review and methodological considerations.

Science progress·2026

Cold Spells, Heat Waves, and Nonoptimal Air Temperature and Risk of Heart Failure Hospitalization in Sweden.

Journal of the American College of Cardiology·2026

Development and Validation of PubMed and Ovid MEDLINE Search Filters for Exposure Pathways Linking Climate Change With Public Health.

Cochrane evidence synthesis and methods·2026

Migration-driven exposome reconfiguration: a predictive, preventive and personalized medicine perspective on cardiometabolic risk.

The EPMA journal·2026

The climate change dilemma of ski destinations: adaptation becomes maladaptation.

Frontiers in sports and active living·2026

Priorities for an African research agenda on climate, environment and maternal, newborn and child health.

Frontiers in global women's health·2026

[Climate action, a clinical lever for mental health].

Revue medicale suisse·2026

Related Experiment Videos

How cells respond and adapt to heat stress through alterations in gene expression

Related Concept Videos

Hsp90 chaperone control over transcriptional regulation by the yeast Slt2(Mpk1)p and human ERK5 mitogen-activated protein kinases (MAPKs).

The Hsp90 chaperone as a promising drug target.

The ZbYME2 gene from the food spoilage yeast Zygosaccharomyces bailii confers not only YME2 functions in Saccharomyces cerevisiae, but also the capacity for catabolism of sorbate and benzoate, two major weak organic acid preservatives.

Increasing Saccharomyces cerevisiae stress resistance, through the overactivation of the heat shock response resulting from defects in the Hsp90 chaperone, does not extend replicative life span but can be associated with slower chronological ageing of nondividing cells.

Chronological lifespan of stationary phase yeast cells; a model for investigating the factors that might influence the ageing of postmitotic tissues in higher organisms.

The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains.

Involvement of NOD1/NF-κB/MAPK pathway in the protective effect of procyanidin B2 against methotrexate-induced nephrotoxicity.

Documented arteriovenous fistula thrill category and Doppler hemodynamics in mature radiocephalic fistulas: A single-center retrospective study.

Diagnostic performance of Node-RADS in assessing regional lymph node metastasis and prognosis in resected gastric cancer.

Coats disease: A narrative review of clinical spectrum, imaging features, and contemporary management.

First-24-hour aspirin exposure and 28-day mortality in critically ill adults with cerebral embolism: A retrospective MIMIC-IV cohort study.

Structural white matter alterations in borderline personality disorder: A narrative review and methodological considerations.

Cold Spells, Heat Waves, and Nonoptimal Air Temperature and Risk of Heart Failure Hospitalization in Sweden.

Development and Validation of PubMed and Ovid MEDLINE Search Filters for Exposure Pathways Linking Climate Change With Public Health.

Migration-driven exposome reconfiguration: a predictive, preventive and personalized medicine perspective on cardiometabolic risk.

The climate change dilemma of ski destinations: adaptation becomes maladaptation.

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How cells respond and adapt to heat stress through alterations in gene expression

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