SARS-CoV-2 Tests: Bridging the Gap between Laboratory Sensors and Clinical Applications

Area of Science:

• Biomedical Engineering
• Infectious Disease Diagnostics
• Immunology

Background:

• Current SARS-CoV-2 detection relies on established nucleic acid and biochemical assays.
• Hospitals and clinical laboratories require robust and efficient testing methods.
• There is a need to bridge the gap between current laboratory practices and emerging diagnostic technologies.

Purpose of the Study:

• To review emerging biosensors for SARS-CoV-2 detection.
• To compare these biosensors with existing biochemical and clinical assays.
• To assess the role of new technologies in determining vaccine effectiveness.

Main Methods:

• Literature review of emerging SARS-CoV-2 biosensor technologies.
• Analysis of current biochemical and nucleic acid amplification methods.
• Review of antibody tests for vaccine efficacy assessment.

Main Results:

• Emerging biosensors show promise for rapid SARS-CoV-2 detection.
• Gaps exist in integrating novel sensors into routine laboratory workflows.
• New technologies are being developed to address assay robustness and speed.

Conclusions:

• Biosensors offer potential advancements in SARS-CoV-2 diagnostics.
• Further research is needed to validate and implement emerging sensor technologies.
• Monitoring vaccine effectiveness can be enhanced with advanced antibody testing methods.