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PET Imaging for Head and Neck Cancers.

Charles Marcus1, Sara Sheikhbahaei2, Veeresh Kumar N Shivamurthy3

  • 1Department of Nuclear Medicine and Molecular Imaging, Emory University Hospital, Atlanta, GA, USA.

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This review covers advances in PET imaging for head and neck cancers. Fluorine-18-fluorodeoxyglucose (18F-FDG) PET/CT and PET/MR imaging offer valuable insights for diagnosis and treatment.

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FDG PETHead and neck cancerNeoplasmPET/CTStaging

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Area of Science:

  • Oncology
  • Nuclear Medicine
  • Radiology

Background:

  • Head and neck cancers are prevalent in the US.
  • 18F-FDG PET/CT is widely used for various clinical applications in these cancers.
  • Investigational PET tracers offer additional diagnostic information, including tumor hypoxia.

Purpose of the Study:

  • To provide a concise review of recent advancements in PET imaging for head and neck cancers.
  • To highlight the utility of 18F-FDG PET/CT and emerging 18F-FDG PET/MR imaging.

Main Methods:

  • Review of recent literature on PET imaging in head and neck oncology.
  • Discussion of the established role of 18F-FDG PET/CT.
  • Exploration of the integration of PET with MR imaging.

Main Results:

  • 18F-FDG PET/CT is integral for staging, treatment planning, and monitoring head and neck cancers.
  • 18F-FDG PET/MR imaging combines high soft-tissue resolution with functional PET data.
  • Emerging PET tracers show promise for detecting radioresistant hypoxic tumors.

Conclusions:

  • PET imaging, particularly 18F-FDG PET/CT and PET/MR, plays a crucial role in managing head and neck cancers.
  • Continued research into novel PET tracers and hybrid imaging techniques will further enhance patient care.
  • Advances in PET imaging improve diagnostic accuracy and treatment strategies for head and neck malignancies.