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Vehicle Control as a Measure of Real-World Driving Performance in Patients With Rheumatoid Arthritis
Ted R Mikuls1, Jennifer Merickel2, Yeongjin Gwon2
1University of Nebraska Medical Center and VA Nebraska-Western Iowa Health Care System, Omaha, Nebraska.
Arthritis Care & Research
|August 16, 2021
Summary
Rheumatoid arthritis (RA) drivers show altered vehicle control compared to healthy individuals. Worsening RA disease activity and physical disability are linked to increased variability in braking, accelerating, and steering, especially on highways.
Area of Science:
- Rheumatology
- Automotive Engineering
- Transportation Safety
Background:
- Rheumatoid arthritis (RA) can impact physical function, potentially affecting driving.
- Objective metrics for assessing driving performance in RA patients are needed.
Purpose of the Study:
- To quantify vehicle control as a measure of driving performance in patients with rheumatoid arthritis (RA).
Main Methods:
- Naturalistic driving assessments using in-car sensors in participants' own vehicles.
- Mixed-effects linear regression models analyzed vehicle control (steering, braking/accelerating variability) stratified by road type.
- RA disease status, activity, and functional status were correlated with driving metrics.
Main Results:
- RA drivers (n=33) exhibited different vehicle control than controls (n=23) across 1,292 driving hours.
- RA drivers showed lower braking/accelerating variability on residential roads and lower steering variability when RA disease activity was low.
- On highways, RA was linked to increased steering variability in patients with moderate/high disease activity.
- Increased RA disease activity and physical disability correlated with higher braking/accelerating variability on highways over 12 weeks.
Conclusions:
- Novel naturalistic driving assessments linked RA and disease severity to aberrant vehicle control.
- Findings highlight the need to correlate driving control patterns with driver risk metrics.
- Real-world driving behavior patterns may inform RA diagnosis and disease activity monitoring.

