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Published on: December 18, 2010
Severe bowel complications in SARS-CoV-2 patients receiving protocolized care
S C Estevez-Cerda1, J A Saldaña-Rodríguez1, A G Alam-Gidi1
1Departamento de Cirugía General, Tecnológico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Mexico.
Severe gastrointestinal complications, including bowel perforations and necrosis, occurred in 10 patients with SARS-CoV-2 infection. This case series highlights a 50% mortality rate and the need for further research into these critical COVID-19 complications.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Surgical Pathology
Background:
- Severe gastrointestinal complications are increasingly recognized in patients with SARS-CoV-2 infection.
- Existing literature lacks detailed case series on these specific complications.
Purpose of the Study:
- To present a case series of patients with SARS-CoV-2 infection who developed severe gastrointestinal complications.
- To contribute to the understanding of gastrointestinal manifestations of SARS-CoV-2.
Main Methods:
- Retrospective review of patients admitted with SARS-CoV-2 infection.
- Inclusion criteria: development of severe gastrointestinal complications.
- Data collection on patient management and surgical interventions.
Main Results:
- Ten out of 905 SARS-CoV-2 patients developed severe gastrointestinal complications.
- Complications included jejunal and colonic perforations, intestinal necrosis.
- Surgical interventions included colectomies and intestinal resections.
- Mortality rate was 50%.
Conclusions:
- Spontaneous bowel perforations and acute mesenteric ischemia are severe, life-threatening complications of SARS-CoV-2.
- Further research is required to identify risk factors and preventive strategies.
- Analysis of treatment protocols' adverse effects is needed.
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