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Updated: Oct 23, 2025

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19
Published on: May 25, 2022
[COVID-19: is transmission through eye contact possible?]
S N Bulgar1, R F Akhmetshin2, E A Abdulaeva1
1Kazan State Medical Academy - branch of Russian Medical Academy of Continuous Professional Education, Kazan, Russia.
Coronavirus can spread through the eyes, with conjunctivitis being a common symptom. While not a primary route, COVID-19 transmission via the eye surface is possible and requires precautions.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Virology
Background:
- Ocular manifestations of COVID-19 are reported, with conjunctivitis being the most frequent.
- The incidence of ocular symptoms in COVID-19 patients ranges from 0.8% to 31.6%.
Purpose of the Study:
- To review scientific literature on the potential transmission of coronavirus, specifically COVID-19, via the ocular surface.
- To analyze the occurrence and detection of SARS-CoV-2 in conjunctival secretions.
Main Methods:
- Systematic review of international and Russian scientific papers.
- Analysis of data on virus detection in conjunctival discharge from COVID-19 patients.
- Inclusion of experimental studies on transconjunctival and respiratory exposure in Rhesus macaques.
Main Results:
- Virus detection in conjunctival cavities was observed in 3.17% of analyzed COVID-19 patients (8 out of 252).
- COVID-19-associated conjunctivitis can be an early or primary symptom, sometimes without visible eye inflammation.
- Experimental exposure confirmed the possibility of SARS-CoV-2 transmission through the conjunctiva.
Conclusions:
- Transmission of COVID-19 through the eye surface is possible, though not considered a major route.
- The conjunctival cavity of infected individuals can serve as a source of SARS-CoV-2.
- Eye protection measures are recommended when handling potentially infected patients.
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