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Published on: September 22, 2023
Correlation of serum calcium with severity of acute ischaemic stroke
Ainan Arshad1, Saad Bin Zafar Mahmood2, Ahmed Ayaz3
1Department of Medicine, Aga khan University, Karachi, Pakistan.
Insights
This study investigated serum calcium levels in acute ischemic stroke patients. Researchers found no significant correlation between serum calcium and stroke severity, despite calcium
Area of Science:
- Neurology
- Biochemistry
Background:
- Stroke is a leading cause of mortality globally, particularly in developing nations.
- Serum calcium has been proposed as a potential factor influencing ischemic stroke.
- Understanding factors affecting stroke severity is crucial for patient outcomes.
Purpose of the Study:
- To investigate the correlation between serum calcium levels and the severity of acute ischemic stroke.
- To analyze the relationship in a specific patient population.
Main Methods:
- Retrospective observational study design.
- Inclusion of 279 patients admitted with acute ischemic stroke.
- Comparison of patient characteristics, including serum calcium and stroke severity scores.
Main Results:
- The study included 162 males with a mean age of 62.4 years.
- Mean albumin-corrected serum calcium was 9.1 (± 5.6) and Scandinavian Stroke Severity score was 33.67 (± 15.2).
- Hypertension and Glasgow Coma Scale (GCS) on admission were associated with increased stroke severity, but serum calcium was not.
Conclusions:
- No significant correlation was found between serum calcium levels and the severity of acute ischemic stroke in this study population.
- Further research may be needed to explore other potential biomarkers or factors influencing stroke severity.
Abstract:
Stroke results in the death of around 6.5 million people annually with a majority of these occurring in developing countries. Serum calcium has been hypothesised to play a significant role in causing ischaemic stroke. This retrospective observational study was conducted to determine the correlation, if any, between serum calcium and the severity of acute ischaemic stroke in our population. Two hundred and seventy-nine patients admitted with acute ischaemic stroke were enrolled in the study. Of the 279 patients 162 (58%) were male and mean age was 62.4 ± 3.8 years. Characteristics of stroke patients were compared with stroke severity. Mean albumin corrected serum calcium and Scandinavian stroke severity score was 9.1 (± 5.6) and 33.67 (± 15.2), respectively. Hypertension and mean GCS on admission were significantly associated with increased stroke severity score. However, no correlation was observed between serum calcium and severity of acute ischaemic stroke.
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