Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cranial Bones: Lateral View01:27

Cranial Bones: Lateral View

3.3K
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
3.3K
Visual System01:26

Visual System

1.1K
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
1.1K
Cranial Bones: Superior and Posterior View01:14

Cranial Bones: Superior and Posterior View

3.6K
The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
3.6K
Parallel Processing01:20

Parallel Processing

374
The brain processes sensory information rapidly due to parallel processing, which involves sending data across multiple neural pathways at the same time. This method allows the brain to manage various sensory qualities, such as shapes, colors, movements, and locations, all concurrently. For instance, when observing a forest landscape, the brain simultaneously processes the movement of leaves, the shapes of trees, the depth between them, and the various shades of green. This enables a quick and...
374
Vision01:24

Vision

57.0K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
57.0K
Cranial Nerves: Types Part I01:14

Cranial Nerves: Types Part I

3.7K
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves, with the first six being essential in sensory perception, motor control, and autonomic functions related to the head and neck.
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
3.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

No evidence for direct physical interaction of 5-HT <sub>2A</sub> -mGluR2 receptors <i>in vitro</i> or <i>in vivo</i>.

bioRxiv : the preprint server for biology·2026
Same author

GPCR Biased Signaling: Opportunities and Challenges.

Biochemistry·2026
Same author

Structural characterization of kappa-opioid receptor dimer in complex with two G proteins.

Nature communications·2026
Same author

Toward a Random Background for Ligand Optimization.

bioRxiv : the preprint server for biology·2026
Same author

De novo design of miniproteins targeting GPCRs.

Nature·2026
Same author

The Selectivity Implications of Docking Libraries with Greater and Lesser Similarities to Bio-like Molecules.

Journal of medicinal chemistry·2026

Related Experiment Video

Updated: Oct 23, 2025

Imaging Neural Activity in the Primary Somatosensory Cortex Using Thy1-GCaMP6s Transgenic Mice
07:04

Imaging Neural Activity in the Primary Somatosensory Cortex Using Thy1-GCaMP6s Transgenic Mice

Published on: January 7, 2019

11.3K

The cranial windows of perception.

Jeffrey F DiBerto1, Bryan L Roth1

  • 1Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599-7365, USA.

Neuron
|August 19, 2021
PubMed
Summary

Psilocybin rapidly promotes new connections in brain cells, potentially explaining its antidepressant effects. This study reveals how psilocybin may support long-lasting mood improvements by enhancing neural plasticity.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Cell Biology

Background:

  • Psilocybin is a psychedelic compound with potential rapid-acting antidepressant properties.
  • Understanding the cellular mechanisms underlying psilocybin's therapeutic effects is crucial.

Purpose of the Study:

  • To investigate the immediate cellular effects of psilocybin on neuronal structure.
  • To explore the link between psilocybin-induced structural changes and its antidepressant actions.

Main Methods:

  • Administration of psilocybin to subjects or in vitro models.
  • Microscopic analysis of neuronal morphology, specifically dendritic spines.
  • Assessment of changes in cortical layer V pyramidal neurons.

Main Results:

More Related Videos

Implantation of a Cranial Window for Repeated In Vivo Imaging in Awake Mice
06:33

Implantation of a Cranial Window for Repeated In Vivo Imaging in Awake Mice

Published on: June 22, 2021

8.0K
A Polished and Reinforced Thinned-skull Window for Long-term Imaging of the Mouse Brain
09:49

A Polished and Reinforced Thinned-skull Window for Long-term Imaging of the Mouse Brain

Published on: March 7, 2012

27.4K

Related Experiment Videos

Last Updated: Oct 23, 2025

Imaging Neural Activity in the Primary Somatosensory Cortex Using Thy1-GCaMP6s Transgenic Mice
07:04

Imaging Neural Activity in the Primary Somatosensory Cortex Using Thy1-GCaMP6s Transgenic Mice

Published on: January 7, 2019

11.3K
Implantation of a Cranial Window for Repeated In Vivo Imaging in Awake Mice
06:33

Implantation of a Cranial Window for Repeated In Vivo Imaging in Awake Mice

Published on: June 22, 2021

8.0K
A Polished and Reinforced Thinned-skull Window for Long-term Imaging of the Mouse Brain
09:49

A Polished and Reinforced Thinned-skull Window for Long-term Imaging of the Mouse Brain

Published on: March 7, 2012

27.4K
  • Psilocybin treatment rapidly increased the formation of dendritic spines.
  • These structural changes were observed in cortical layer V pyramidal neurons.
  • The findings suggest a direct cellular impact of psilocybin.

Conclusions:

  • Psilocybin's rapid antidepressant effects may be mediated by the quick induction of dendritic spine formation.
  • This structural plasticity in cortical neurons could be a key cellular substrate for psilocybin's therapeutic benefits.
  • Further research is warranted to fully elucidate the neurobiological underpinnings of psilocybin therapy.