What can artificial intelligence and machine learning tell us? A review of applications to equine biomechanical...

Artificial intelligence (AI) and machine learning (ML) are fascinating interdisciplinary scientific domains where machines are provided with an approximation of human intelligence. The conjecture is that machines are able to learn from existing examples, and employ this accumulated knowledge to fulfil challenging tasks such as regression analysis, pattern classification, and prediction. The horse biomechanical models have been identified as an alternative tool to investigate the effects of mechanical loading and induced deformations on the tissues and structures in humans. Many reported investigations into bone fatigue, subchondral bone damage in the joints of both humans and animals, and identification of vital parameters responsible for retaining integrity of anatomical regions during normal activities in all species are heavily reliant on equine biomechanical research. Horse racing is a lucrative industry and injury prevention in expensive thoroughbreds has encouraged the implementation of various measurement techniques, which results in massive data generation. ML substantially accelerates analysis and interpretation of data and provides considerable advantages over traditional statistical tools historically adopted in biomechanical research. This paper provides the reader with: a brief introduction to AI, taxonomy and several types of ML algorithms, working principle of a feedforward artificial neural network (ANN), and, a detailed review of the applications of AI, ML, and ANN in equine biomechanical research (i.e. locomotory system function, gait analysis, joint and bone mechanics, and hoof function). Reviewing literature on the use of these data-driven tools is essential since their wider application has the potential to: improve clinical assessments enabling real-time simulations, avoid and/or minimize injuries, and encourage early detection of such injuries in the first place.