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Subungual Onycholemmal Cysts: A Case Report.
Erika Lydrup1, Anette Pedersen Pilt2, Volker-Jürgen Schmidt1
1Department of Plastic Surgery and Breast Surgery, Zealand University Hospital, Roskilde, Denmark.
Case Reports in Dermatology
|August 20, 2021
Summary
Subungual onycholemmal cysts (SOCs) are rare nail conditions. This case report highlights how SOCs can mimic melanoma, emphasizing the importance of histopathological examination for accurate diagnosis.
Area of Science:
- Dermatology
- Pathology
Background:
- Subungual onycholemmal cysts (SOCs) are uncommon nail abnormalities.
- Clinical presentations of SOCs are diverse, including onychodystrophy, nail ridging, pigmentation, and thickening.
- Often, SOCs are asymptomatic incidental findings.
Observation:
- A case report details a woman presenting with toenail pigmentation, initially suspected to be melanoma.
- The patient's clinical presentation mimicked a more serious condition.
Findings:
- Histopathological examination unexpectedly revealed Subungual onycholemmal cysts (SOCs).
- This finding underscores the potential for SOCs to present with concerning clinical signs.
Implications:
- Accurate diagnosis of SOCs is crucial, as they can mimic melanoma.
- Histopathological analysis is essential for differentiating SOCs from other nail disorders.
- Understanding the varied clinical and histological features of SOCs aids in diagnosis and management.

