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Two amide glycosides from Portulaca oleracea L. and its bioactivities
Xilong Liu1, Haibo Wu2, Xiaojun Tao1
1School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, P.R. China.
Natural Product Research
|August 20, 2021
Abstract:
Two novel amide glycosides, named oleraciamide E (1) and oleraciamide F (2), were isolated from the Portulaca oleracea L. Their structures were determined by means of 1D and 2D NMR spectroscopic and UHPLC-ESI-TOF-MS methods. Oleraciamide E (1) exhibited anticholinesterase activity with IC50 values of 52.43 ± 0.33 μM, and presented scavenging activity in 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical quenching assay, with the IC50 values of 24.64 ± 0.33 μM.

