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Published on: December 1, 2023
Cirrhotic Cardiomyopathy and Cardiac Failure after Liver Transplantation: A Case Series
Robert A Mester1, W David Stoll1
1Department of Anesthesia and Perioperative Medicine-Medical University of South Carolina, Charleston, South Carolina.
Insights
Preoperative cardiac assessment for liver transplant patients remains debated. This case series highlights that normal preoperative tests do not rule out postoperative cardiac dysfunction, emphasizing the need for vigilant monitoring.
Area of Science:
- Cardiology
- Transplantation Medicine
- Critical Care Medicine
Background:
- Preoperative cardiac functional assessment is crucial but debated in liver transplantation.
- Significant cardiac events contribute to a notable percentage of mortality post-transplant.
- Current guidelines and practices for cardiac evaluation prior to liver transplant vary.
Observation:
- A case series of three patients undergoing orthotopic liver transplantation is presented.
- All patients exhibited normal preoperative cardiac assessments with no significant hemodynamic abnormalities.
- Postoperatively, all three patients developed significant cardiac dysfunction.
Findings:
- Each patient's postoperative cardiac failure stemmed from distinct and unrelated diagnoses.
- The findings suggest that preoperative cardiac assessments may not always predict postoperative cardiac complications.
- The diverse etiologies of cardiac failure underscore the complexity of cardiac management in liver transplant recipients.
Implications:
- This case series suggests that normal preoperative cardiac function does not preclude the development of severe postoperative cardiac dysfunction.
- It highlights the potential limitations of current preoperative cardiac assessment protocols in identifying all at-risk liver transplant candidates.
- Further research is warranted to refine cardiac risk stratification and postoperative monitoring strategies in liver transplantation.
Abstract:
Preoperative cardiac functional assessment has been a long-debated topic in liver transplantation. Debate continues to exist regarding the use of invasive cardiac studies, and the utility of each prior to transplant. Despite the debate, a 7% mortality can be attributed to significant cardiac events. We present a case series of 3 patients who underwent orthotopic liver transplantation and developed significant cardiac dysfunction postoperatively. All preoperative cardiac assessments in each patient were normal with no hemodynamically significant abnormalities. Interestingly enough, each patient developed cardiac failure due to completely different diagnoses.
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