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Handwriting graphical parameters analysis in Posterior Cortical Atrophy: A case report
Alexandra Videt-Dussert1, Alexandra Plonka2, Alexandre Derreumaux3
1Université Côte d'Azur, Département d'Orthophonie de Nice, Nice, France.
Clinical Neurology and Neurosurgery
|August 21, 2021
Summary
Posterior Cortical Atrophy (PCA) diagnosis can be improved by analyzing handwriting kinematics. This study found unique writing patterns in PCA patients, differentiating them from healthy individuals and Alzheimer's Disease patients.
Area of Science:
- Neuroscience
- Neurology
- Clinical Diagnostics
Background:
- Posterior Cortical Atrophy (PCA) is a rare neurodegenerative syndrome affecting visual functions due to occipital atrophy.
- Inconsistent terminology complicates PCA diagnosis, often leading to delays.
Observation:
- A 76-year-old patient with PCA presented with difficulties in reading, writing, and daily tasks.
- The study focused on evaluating kinematic writing parameters: jerk, velocity, and pressure.
Findings:
- PCA patients exhibited a distinct kinematic writing profile compared to healthy controls and Alzheimer's Disease patients.
- Analysis included linguistic, cognitive-non-linguistic, and non-cognitive-non-linguistic graphical tasks.
Implications:
- Handwriting kinematic analysis offers a novel approach for the clinical diagnosis of Posterior Cortical Atrophy.
- This method could aid in earlier and more accurate identification of PCA, improving patient management.

