[Decreased G-actin content in cells at injury]

The content of G-actin was measured in aqueous extracts of rat macrophages and human lymphocytes at hyperthermia and hypoxia. The G-actin content in altered cells decreases the greater the stronger the injury. This decrease correlates well with the data on visual estimation of cell light diffusing. A possible contribution of actin polymerization and its interaction with proteins in the colloidal reactions of altered protoplasm is discussed.