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Updated: Oct 23, 2025

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Scheduled percutaneous endoscopic gastrostomy tube replacement did not reduce PEG-related complications
Wisam Sbeit1,2, Anas Kadah1,2, Amir Shahin1,2
1Department of Gastroenterology, Galilee Medical Center, Nahariya, Israel.
Background:
Percutaneous endoscopic gastrostomy (PEG) tube insertion is used for enteral nutrition. Each manufacturer has its own instructions for planned tube replacement. Accordingly, caregivers have adopted the policy of elective change at a fixed period of time (3-6 months).
Aim:
The current study aimed to assess whether retained PEG for more than 6 months was associated with a higher rate of PEG-related complications.
Methods:
A retrospective single-center study included all patients who underwent PEG insertion were included in the study.
Results:
Overall, 303 patients were included, 48 patients (16.2%) had PEG tube replacement. Peristomal PEG tube leak was the commonest complication, occurring in 20 patients (41.7%), followed by dislodgement in 18 patients (37.5%) and obstruction in 10 patients (20.8%). Among the patients with a leak, it occurred within and beyond 6 months from PEG insertion in 40 and 60% of patients, respectively (OR 0.68, 95% CI 0.21-2.18, p = .57). Similarly, 50% of patients had PEG tube obstruction within 6 months and 50% had it beyond 6 months from insertion (OR 1.46, 95% CI 0.34-6.26, p = .72). Moreover, there was no difference in PEG dislodgement after PEG insertion within or beyond 6 months (nine patients, 50% vs. nine patients, 50%), respectively, (OR 1.37, 95% CI 0.42-4.47, p = .76).
Conclusion:
Retained PEG tubes for more than 6-months were not associated with more PEG-tube-related complications.
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