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Updated: Oct 23, 2025

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
Published on: November 4, 2015
Evaluation and management of patients with chronic thromboembolic pulmonary hypertension - consensus statement from
Marc de Perrot1, Deepa Gopalan2, David Jenkins3
1Division of Thoracic Surgery, Toronto General Hospital, Toronto, Ontario, Canada.
Insights
This consensus statement addresses chronic thromboembolic pulmonary hypertension (CTEPH) evaluation and management. It synthesizes expert opinion and literature review due to limited comparative trials.
Area of Science:
- Cardiology
- Pulmonology
- Medical Guidelines
Background:
- Chronic thromboembolic pulmonary hypertension (CTEPH) requires standardized evaluation and management protocols.
- The International Society for Heart and Lung Transplantation (ISHLT) identified the need for a consensus statement.
Purpose of the Study:
- To develop a comprehensive consensus statement on the evaluation and management of CTEPH patients.
- To provide guidance for clinicians based on current evidence and expert consensus.
Main Methods:
- Formation of expert working groups under ISHLT.
- Extensive literature search conducted by each working group.
- Consolidation of findings into a single document, reviewed by all experts.
Main Results:
- The document represents a literature review incorporating expert opinion.
- Key points are summarized within each section for clarity.
- The approach acknowledges the scarcity of comparative trials in CTEPH.
Conclusions:
- The consensus statement offers a framework for CTEPH patient care.
- It highlights areas where further research is needed.
- This guideline aims to improve clinical decision-making for CTEPH.
Abstract:
ISHLT members have recognized the importance of a consensus statement on the evaluation and management of patients with chronic thromboembolic pulmonary hypertension. The creation of this document required multiple steps, including the engagement of the ISHLT councils, approval by the Standards and Guidelines Committee, identification and selection of experts in the field, and the development of 6 working groups. Each working group provided a separate section based on an extensive literature search. These sections were then coalesced into a single document that was circulated to all members of the working groups. Key points were summarized at the end of each section. Due to the limited number of comparative trials in this field, the document was written as a literature review with expert opinion rather than based on level of evidence.
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